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depression 4

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Association of maternal depression with dietary intake, growth, and development of preterm infants: a

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 533-541 doi: 10.1007/s11684-017-0591-y

Abstract:

This study aimed to explore the association of maternal depression with nutrient intake, growth, and(64), non-depression-preterm (70), depression-fullterm (36), and depression-preterm (31).A multivariate analysis was used to evaluate the effects of maternal depression and preterm birth onThe energy, protein, and carbohydrate intake in the depression group was lower than the recommended amountsThe depression preterm groups indicated the lowest Z-scores for length and weight and the lowest Bayley-III

Keywords： maternal depression     preterm     infant     nutrition     growth     development    

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Astrocytes in depression and Alzheimer’s disease

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 829-841 doi: 10.1007/s11684-021-0875-0

Abstract: clinical cases, multiple chronic brain diseases may cause psychosocial and cognitive impairment, such as depressionFor years, complex pathological conditions driven by depression and AD have been widely perceived toInterestingly, correlational research on depression and AD has shown that depression might be a prodromeMounting evidence has shown that astrocytic dysfunction is involved in the progression of depressionherein review the current findings on the roles and mechanisms of astrocytes in the development of depression

Keywords： astrocytes     depression     Alzheimer’s disease     roles     mechanisms    

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Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Frontiers of Medicine 2018, Volume 12, Issue 6,   Pages 678-687 doi: 10.1007/s11684-018-0671-7

Abstract:

Type 2 diabetes (T2D) has been associated with a high prevalence of depression.The T2D_GRS was found to be associated with depression with an OR of 1.21 (95% CI: 1.07–1.37) after adjustmentsT2D_GRS as the IV, we similarly found a causal relationship between genetically determined T2D and depressionThough we found no association between the combined effect of the genetic IVs for T2D and depressionwith Egger MR (OR: 0.95, 95% CI: 0.42–2.14), we found an association for T2D and depression with IVW

Keywords： causal modeling     depression     Mendelian randomization     type 2 diabetes    

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Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 729-746 doi: 10.1007/s11684-022-0978-2

Abstract: The effect of anti-programmed cell death 1 (anti-PD-1) immunotherapy is limited in patients with hepatocellular carcinoma (HCC). Yes-associated protein 1 (YAP1) expression increased in liver tumor cells in early HCC, and Akkermansia muciniphila abundance decreased in the colon. The response to anti-PD-1 treatment is associated with A. muciniphila abundance in many tumors. However, the interaction between A. muciniphila abundance and YAP1 expression remains unclear in HCC. Here, anti-PD-1 treatment decreased A. muciniphila abundance in the colon, but increased YAP1 expression in the tumor cells by mice with liver tumors in situ. Mechanistically, hepatocyte-specific Yap1 knockout (Yap1LKO) maintained bile acid homeostasis in the liver, resulting in an increased abundance of A. muciniphila in the colon. Yap1 knockout enhanced anti-PD-1 efficacy. Therefore, YAP1 inhibition is a potential target for increasing A. muciniphila abundance to promote anti-PD-1 efficacy in liver tumors. Dihydroartemisinin (DHA), acting as YAP1 inhibitor, increased A. muciniphila abundance to sensitize anti-PD-1 therapy. A. muciniphila by gavage increased the number and activation of CD8+ T cells in liver tumor niches during DHA treatment or combination with anti-PD-1. Our findings suggested that the combination anti-PD-1 with DHA is an effective strategy for liver tumor treatment.

Keywords： hepatocellular carcinoma     YAP1     Akkermansia muciniphila     anti-PD-1     dihydroartemisinin     bile acid    

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Detection of maternal serum thromboxane B2 in different durations of pregnancy and prediction of preeclampsia

Geqing XIA MD, Zehua WANG MD, Li ZOU MD, Chaoying WU MS, Yu HU MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 235-240 doi: 10.1007/s11684-010-0002-0

Abstract: This study was aimed to detect maternal serum levels of thromboxane B2 (TXB2) in different durationsMaternal serum levels of TXB2 were measured by enzyme-linked immunoassay.There was a statistical significance in maternal TXB2 levels between two different gestational stages(<0.01). (3) The levels of maternal serum TXB2 were slightly higher in the case group than in theHigher levels of maternal serum TXB2 were detected a long time before clinical symptoms appeared.

Keywords： thromboxane B2     preeclampsia    

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Molecular regulation and genetic improvement of seed oil content in

Wei HUA,Jing LIU,Hanzhong WANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 3,   Pages 186-194 doi: 10.15302/J-FASE-2016107

Abstract: regulation of oil content in , including genetics, biosynthesis pathway, transcriptional regulation, maternal

Keywords： breeding     maternal effects     oilseed rape     QTL    

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Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 227-239 doi: 10.1007/s11684-021-0896-8

Abstract: adult hippocampal neurogenesis (AHN), whereas promoting AHN can increase stress resilience against depressionThe nonpsychoactive phytocannabinoid cannabidiol (CBD) has been shown to be effective against depressionThese results revealed a previously unknown neural mechanism for neural differentiation and AHN in depression

Keywords： cannabidiol     depression     radial neural stem cells     neurogenesis    

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Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats

Qihui Luo,Zhengli Chen,Anchun Cheng,Mingshu Wang,Jing Fang,Xi Peng,Li Tang

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 82-89 doi: 10.1007/s11684-015-0376-0

Abstract: In this study, the maternal toxicity, embryo-fetal developmental toxicity and teratogenicity were studiedat a dose of 200 mg/(kg·d) (i.e., 40 times the effective dose in rats), Metacavir shows some maternal

Keywords： deoxyguanosine analogue     Metacavir     pregnancy     maternal toxicity     embryo toxicity     teratogenicity    

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Technologies for Pipelining High-Pour-Point and Viscous Crudes and Their Development

Zhang Jinjun

Strategic Study of CAE 2002, Volume 4, Issue 6,   Pages 71-76

Abstract: The up-to-date research and application of technologies for pour point depression and drag reduction

Keywords： pipelining     paraffin-base crude     heavy crude     pour point depression     drag reduction     chemical additives    

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Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 193-198 doi: 10.1007/s11684-020-0772-y

Abstract: The aim of this study was to investigate the clinical characteristics of neonates born to SARS-CoV-2 infected mothers and increase the current knowledge on the perinatal consequences of COVID-19. Nineteen neonates were admitted to Tongji Hospital from January 31 to February 29, 2020. Their mothers were clinically diagnosed or laboratory-confirmed with COVID-19. We prospectively collected and analyzed data of mothers and infants. There are 19 neonates included in the research. Among them, 10 mothers were confirmed COVID-19 by positive SARS-CoV-2 RT-PCR in throat swab, and 9 mothers were clinically diagnosed with COVID-19. Delivery occurred in an isolation room and neonates were immediately separated from the mothers and isolated for at least 14 days. No fetal distress was found. Gestational age of the neonates was 38.6±1.5 weeks, and average birth weight was 3293±425 g. SARS-CoV-2 RT-PCR in throat swab, urine, and feces of all neonates were negative. SARS-CoV-2 RT-PCR in breast milk and amniotic fluid was negative too. None of the neonates developed clinical, radiologic, hematologic, or biochemical evidence of COVID-19. No vertical transmission of SARS-CoV-2 and no perinatal complications in the third trimester were found in our study. The delivery should occur in isolation and neonates should be separated from the infected mothers and care givers.

Keywords： coronavirus disease 2019     severe acute respiratory syndrome-associated coronavirus     maternal-infant infection    

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The characteristics of Paleozoic marine hydrocarbon accumulation in China

Kang Yuzhu

Strategic Study of CAE 2010, Volume 12, Issue 5,   Pages 11-17

Abstract:

In the Tarim petroleum geology investigation from 1970 to 1978, the author proposed for the first time that there was developed source rock in the Paleozoic era. A great breakthrough of Paleozoic marine hydrocarbon field was achieved in Shacan No. 2 well in 1982. Through deep research of many Paleozoic marine hydrocarbon fields, the author proposed Paleozoic marine hydrocarbon accumulation theory in 1992, which includes superposition composite basin accumulation, multi-era and multi-layer series petroleum generation, multi-stage accumulation, multi-era and multi-type reservoir-seal assemblage, multi-accumulation model and that hydrocarbon is mainly distributed around paleo-uplift, paleo-slope, fault zone and unconformity.

Keywords： Paleozoic era     marine hydrocarbon field     basin     uplift     depression     hydrocarbon distribution    

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The relationship between maternal environmental factors and fetus congenital heart disease

Liu Yan,Huang Peng,Sun Xiaoru,Lin Ning, Yu Rongbin,Shi Hui,Wang Lijuan

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 41-44

Abstract:

Objective：To study the relationship between maternal risk factors and fetus congenital heart diseasedeterminants associated with CHD of children(P<0.05).Conclusions：It is particularly important of maternal

Keywords： fetus     congenital heart disease     environmental factors    

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Formation conditions of shale oil and gas in Bonan subsag, Jiyang Depression

Zhang Shanwen,Wang Yongshi,Zhang Linye,Li Zheng,Zhu Jiajun,Gong Jianqiang,Hao Yunqing

Strategic Study of CAE 2012, Volume 14, Issue 6,   Pages 49-55

Abstract: , it is concluded that the shale of Paleogene Es1, Lower Es3 and Upper Es4 in Bonan sub-sag, Jiyang Depression

Keywords： shale oil and gas     Paleogene     terrestrial shale     mineral composition     organic carbon content    

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-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and the Maternal–Fetal Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract: explored ACE2 and TMPRSS2 expression patterns in peri-implantation embryos and the maternalweek syncytiotrophoblast (STB_8W) cells and 24-week extravillous trophoblast (EVTs_24W) cells in the maternal

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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Title Author Date Type Operation

Association of maternal depression with dietary intake, growth, and development of preterm infants: a

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Journal Article

Astrocytes in depression and Alzheimer’s disease

Journal Article

Type 2 diabetes is causally associated with depression: a Mendelian randomization analysis

Liping Xuan, Zhiyun Zhao, Xu Jia, Yanan Hou, Tiange Wang, Mian Li, Jieli Lu, Yu Xu, Yuhong Chen, Lu Qi, Weiqing Wang, Yufang Bi, Min Xu

Journal Article

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma

Journal Article

Detection of maternal serum thromboxane B2 in different durations of pregnancy and prediction of preeclampsia

Geqing XIA MD, Zehua WANG MD, Li ZOU MD, Chaoying WU MS, Yu HU MD,

Journal Article

Molecular regulation and genetic improvement of seed oil content in

Wei HUA,Jing LIU,Hanzhong WANG

Journal Article

Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation

Journal Article

Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats

Qihui Luo,Zhengli Chen,Anchun Cheng,Mingshu Wang,Jing Fang,Xi Peng,Li Tang

Journal Article

Technologies for Pipelining High-Pour-Point and Viscous Crudes and Their Development

Zhang Jinjun

Journal Article

Clinical characteristics of 19 neonates born to mothers with COVID-19

Wei Liu, Jing Wang, Wenbin Li, Zhaoxian Zhou, Siying Liu, Zhihui Rong

Journal Article

The characteristics of Paleozoic marine hydrocarbon accumulation in China

Kang Yuzhu

Journal Article

The relationship between maternal environmental factors and fetus congenital heart disease

Liu Yan,Huang Peng,Sun Xiaoru,Lin Ning, Yu Rongbin,Shi Hui,Wang Lijuan

Journal Article

Formation conditions of shale oil and gas in Bonan subsag, Jiyang Depression

Zhang Shanwen,Wang Yongshi,Zhang Linye,Li Zheng,Zhu Jiajun,Gong Jianqiang,Hao Yunqing

Journal Article

-2 Entry Factors: ACE2 and TMPRSS2 Are Expressed in Peri-Implantation Embryos and the Maternal–Fetal

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article